Analgesics with ibuprofen are not recommended for men.
One of the authors of the study is Bernard изeguet from the Institute for Environmental Research and Labor Hygiene in France. Together with a group of French and Danish scientists, they studied the effects of taking popular lung painkillers containing paracetamol and ibuprofen. The first results, published some time ago, showed that the use of such drugs by pregnant mothers affects the testicles of their boys.
Kernels are not responsible only for the production of sperm. This is also where testosterone, the hormonal essence of masculinity, is secreted. Therefore, painkillers are “anti-manic” - because they can disrupt the production of this hormone in the body, - says David M. Christensen, co-author of the study from the University Hospital of Copenhagen.
Pain medications that contain ibuprofen can be taken by athletes before the onset of pain, in order to be able to protect themselves from excessive effort. The researchers collected 31 volunteers, men aged 18 to 35 years. 14 of them received a dose of 600 mg of substance twice a day. The rest received a placebo. After 14 days, it was found that those who took the level of lutropin (a hormone that stimulates testosterone production in the testicles) synchronized with the level of ibuprofen in the blood. At the same time, the ratio of testosterone to lutropin has dramatically decreased - this is a sign of poorly functioning testicles.
This defect in the reproductive system is called hypogonadism and leads to infertility, depression and an increased risk of cardiovascular disease.
Worldwide, according to WHO, one in four families cannot wait for children after five years of continuous efforts. Another study shows that about 15% of couples worldwide in 2010 were fruitless. In about 30-50% of cases, the problem lies with the men. In addition, an analysis was published in the “Renewal of Human Reproduction”, according to which the quality and number of spermatozoa over the past 40 years in men decreased by 52%, in turn, by 52%.
Fertility related Erma Z. Drobnis from the University of Missouri comments on the research findings, explaining that most drugs are not tested for the effect on male fertility before release.
“There is evidence that some drugs are harmful to the reproductive system, including those that contain testosterone, opioids, antidepressants, psychotropic drugs, painkillers, even those that are sold without a prescription,” he explains. - The problem is that it is rare for someone to prescribe them to patients about the consequences.
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